NEET 2023 · Class 12

Molecular Basis of Inheritance

In which disorder change of single base pair in the gene for beta globin chain results in change of glutamic acid to valine?

  1. (A)Thalassemia
  2. (B)Sickle cell anemia
  3. (C)Haemophilia
  4. (D)Phenylketonuria

The NCERT line that answers it

Verbatim line

A classical example of point mutation is a change of single base pair in the gene for beta globin chain that results in the change of amino acid residue glutamate to valine.

Chapter
Molecular Basis of Inheritance
Section
5.6.1 Mutations and Genetic Code
Page
18
Words matched
43 of 43

The answer appears as a continuous sentence in NCERT. This is that sentence.

How this line gives the answer

4286, emb=0.8122, combined=0.6587). Verified: high — The span explicitly states that the described point mutation 'results into a diseased condition called as sickle cell anemia', which directly matches the correct answer and distinguishes it from other options.

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