NEET 2017 · Class 12

Principles of Inheritance and Variation

Thalassemia and sickle cell anemia are caused due to a problem in globin molecule synthesis. Select the correct statement :

  1. (A)Both are due to a quantitative defect in globin chain synthesis
  2. (B)Thalassemia is due to less synthesis of globin molecules
  3. (C)Sickle cell anemia is due to a quantitative problem of globin molecules
  4. (D)Both are due to a qualitative defect in globin chain synthesis

The NCERT line that answers it

Verbatim line

Thalassemia differs from sickle-cell anaemia in that the former is a quantitative problem of synthesising too few globin molecules while the latter is a qualitative problem of synthesising an incorrectly functioning globin.

Chapter
Principles of Inheritance and Variation
Section
4.8.2 Mendelian Disorders
Page
24
Words matched
32 of 32

The answer appears as a continuous sentence in NCERT. This is that sentence.

How this line gives the answer

0, emb=1.0, combined=1.0). Verified: high — The span explicitly states 'Thalassemia is a quantitative problem of synthesising too few globin molecules', which directly matches option B and distinguishes it from sickle-cell anemia as a qualitative defect.

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