NEET 2021 · Class 12

Biotechnology and its Applications

With regard to insulin choose correct options. (a) C-peptide is not present in mature insulin. (b) The insulin produced by rDNA technology has C-peptide. (c) The pro-insulin has C-peptide. (d) A-peptide and B-peptide of insulin are interconnected by disulphide bridges. Choose the correct answer from the options given below.

  1. (A)(b) and (d) only
  2. (B)(b) and (c) only
  3. (C)(a), (c) and (d) only
  4. (D)(a) and (d) only

The NCERT line that answers it

Verbatim line

In mammals, including humans, insulin is synthesised as a pro-hormone (like a pro-enzyme, the pro-hormone also needs to be processed before it becomes a fully mature and functional hormone) which contains an extra stretch called the **C peptide**.

Chapter
Biotechnology and its Applications
Section
10.2.1 Genetically Engineered Insulin

The answer appears as a continuous sentence in NCERT. This is that sentence.

How this line gives the answer

0, emb=1.0, combined=1.0). Verified: high — The span explicitly states 'This C peptide is not present in the mature insulin', which directly supports option (a), and mentions insulin is synthesized as a pro-hormone containing C peptide, supporting option (c). Combined with the earlier statement about disulphide bridges linking chains A and B, all three facts needed for option C are present.

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